Journal Articles
- F. E. Kapucu, I. Tujula, T-K Pakarinen, O. Kulta, L. Sukki, T. Ryynänen, H. Gram, V. Vuolanto, A. Vinogradov, J. Kreutzer, P. H. Jensen, P. Kallio, S. Narkilahti “Human Tripartite Cortical Network Model for Temporal Assessment of Alpha-Synuclein Aggregation and Propagation in Parkinson’s Disease,” npj Parkinson’s Disease 10, 138 Jun 2024. https://doi.org/10.1038/s41531-024-00750-x
- A. Vinogradov, F. E. Kapucu, S. Narkilahti “Exploring Kainic Acid-Induced Alterations in Circular Tripartite Networks with Advanced Analysis Tools”, eNeuro 11, 7 Jul 2024 ENEURO.0035-24.2024; https://doi.org/10.1523/ENEURO.0035-24.2024
- L. Isosaari, H. Vuorenpää, A. Yrjänäinen, F. E. Kapucu, M. Kelloniemi, T-K Pakarinen, S. Miettinen, S. Narkilahti “Simultaneous Induction of Vasculature and Neuronal Network Formation on a Chip Reveals a Dynamic Interrelationship between Cell Types,” Cell Communication and Signalling, 21, 132 Jun 2023 https://doi.org/10.1186/s12964-023-01159-4
- F. E. Kapucu, A. Vinogradov, T. Hyvärinen, L. Ylä-Outinen, S. Narkilahti “Comparative Microelectrode Array Data of the Functional Development of hPSC-derived and Rat Neuronal Networks,” Scientific Data, 9, 120 Mar 2022 https://doi.org/10.1038/s41597-022-01242-4
- R. Mzezewa, J. Lotila, H. Kiiski, A. Vinogradov, F. E. Kapucu, J. Peltola, S. Hagman, S. Narkilahti “A Kainic Acid-induced Seizure Model in Human Pluripotent Stem Cell-derived Cortical Neurons for Studying the Role of IL-6 in the Functional Activity,” Stem Cell Research, 102665 Jan 2022 https://doi.org/10.1016/j.scr.2022.102665
- M. Ristola, C. Fedele, S. Hagman, L. Sukki, F. E. Kapucu, R. Mzezewa, T. Hyvärinen, P. Kallio, A. Priimagi, S. Narkilahti “Directional Growth of Human Neuronal Axons in a Microfluidic Device with Nanotopography on Azobenzene-Based Material,” Advanced Materials Interfaces, 8, 2100048, May 2021. https://doi.org/10.1002/admi.202100048
Abstracts
- Isosaari, O. Kulta, N. Förster, O. Junnila, H. Vuorenpää, A. Yrjänäinen, F. E. Kapucu, K. Rautajoki, S. Miettinen, S. Narkilahti, “Development of biomimetic glioma-on-chip containing neuronal and vascular networks to study tumor–cell interactions,” presented at Vis à vis in the Brain: The Neuron-Glia Interface, Freiburg, Germany, Sep. 2023, 1 page.
- F. E. Kapucu, I. Tujula, O. Kulta, L. Sukki, V. Vuolanto, A. Vinogradov, P. Kallio, S. Narkilahti, “In vitro α–synuclein aggregation and propagation model,” presented at International Congress of Parkinson’s Disease and Movement Disorders 2023, Copenhagen, Denmark, Aug. 2023, 1 page. (Selected as TOP ABSTRACT)
- F. E. Kapucu, I. Tujula, O. Kulta, L. Sukki, V. Vuolanto, A. Vinogradov, P. Kallio, S. Narkilahti, “Human Cortical Neuronal Networks in Microelectrode Embedded Microphysiological System to Study Functional Alterations during Alpha-Synuclein Aggregation and Propagation as Model for Parkinson’s Disease,” presented at Microphysiological Systems World Summit 2023, Berlin, Germany, Jun. 2023, 1 page.
- L. Isosaari, H. Vuorenpää, A. Yrjänäinen, F. E. Kapucu, M. Kelloniemi, T-K Pakarinen, S. Miettinen, S. Narkilahti “Simultaneous Induction of Vasculature and Neuronal Network Formation on a Chip Reveals a Dynamic Interrelationship between Cell Types,” presented at Microphysiological Systems World Summit 2023, Berlin, Germany, Jun. 20223, 1 page.
- F. E. Kapucu, I. Tujula, A. Vinogradov, O. Kulta, S. Narkilahti, “Parkinson’s-on-Chip Model: Screening the activity and its propagation of hPSC-derived neurons during α-synuclein aggregation on MEA embedded microfluidic chips,” presented at MEA Meeting 2022, Tuebingen, Germany, Jul. 2022, 1 page.
- A. Vinogradov, F. E. Kapucu, T. Hyvärinen, S. Narkilahti, “Openly available MEA dataset from hPSC-derived and rat cortical networks and associated data analysis pipeline,” presented at MEA Meeting 2022, Tuebingen, Germany, Jul. 2022, 1 page.
- F. E. Kapucu, I. Tujula, A. Vinogradov, O. Kulta, S. Narkilahti, “Microfluidic chips with embedded microelectrode arrays for studying “prion-like” propagation of alpha-synuclein aggregates,” The European Organ-on-Chip Society (EUROoCS) Conference 2022, Grenoble, France Jul. 2022, 1 page.
- A. Vinogradov, F. E. Kapucu, S. Narkilahti, “An Analysis Pipeline for Signaling of Human Stem Cell Derived Neurons in a Microfluidics Platform with an Embedded Microelectrode Array,” presented at 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Virtual Conference, Nov. 2021, 1 page.
- O. Kulta, F. E. Kapucu, L. Koistinen, L. Sukki, P. Kallio, S. Narkilahti, ”Analyzing Unidirectional Axonal Growth on Microfluidic Devices,” presented at The European Organ-on-Chip Society (EUROoCS) Conference 2021, Virtual Conference, Jul. 2021, 1 page
- I. Tujula, F. E. Kapucu, L. Sukki, P. Kallio, S. Narkilahti, ”Guided Axonal Growth on a Microfluidic Device for Studying the Spread of Parkinson’s Disease Pathology and Its Effects on Neuronal Functionality,” presented at The International Society for Stem Cell Research (ISSCR) Conference 2021, Virtual Conference, Jun. 2021, 1 page